AR









Dialysis practice art

Influence of design on membrane performance

  • Symmetric Membrane fibers

    Symmetric membranes, which can be derived either from cellulose or entirely from synthetic polymers, have a homogeneous configuration throughout the membrane wall, with both the inner and outer layers usually containing similar pore sizes.

  • Asymmetric membranes

    They synthetic polymers only, and have a thin innerselective layer and an outer thick support layer
    Almost all membranes made of polysulfone (PSf) or polyethersulfone (PES) have this type of structure.
    Diffusive resistance to small molecules due to the fiber wall being thick can be compensated by increasing porosity within the support layer.
    Membranes made of polyethersulfone/PVP/polyamide (PEPA) contain three layers, with the outer layer providing mechanical stability

    RIPPLED VERSUS STRAIGHT HOLLOW FIBERS

  • Rippled hollow fibers

    Cellulose derived fibers are naturally wave like (Moire effect)
    Synthetic fibers may be crimped to produce a rippled pattern that more evenly distributes the flow of dialysate.
    Such a design prevents contact or excess packing among fibers and thus allows for better matching of blood and dialysate flows across all sections of the fiber bundle.

  • Cutting edge

    After the membrane fibers are secured within the potting material
    They are opened by cutting them in a manner that produces a smooth and flat surface
      Smooth cutting for
    • preventing hemolysis
    • blood clotting
    • retention of residual blood

    • damag 1
    Dialysis applied science

    common diaysis subjects

    Web Development
    compare two dialyzers
    you can compare different dialyzer such the type, urea clearance on different blood flow, priming volume
    Web Development
    Dialyzer Selection
    Get dialyzers which have certain criteria such as surface area, urea clearance, blood volume, UF Coefficient, Mode of Sterilization and Membrane Type
    Web Development
    dialysis basic concepts
    some concepts to be in mind when dealing with dialysis on real practice
    Web Development
    dialyzer biocompatibility
    The level of complement activation produced by a membrane is considered a significant determinant of membrane biocompatibilit
    Web Development
    Dialyzer Info
    basic information about the dialyzers related to type, Surface area , urea and creatinine clearance
    Web Development
    DRUG DIALYZABILITY
    Check wether the drug is dialyzable or not
    Web Development
    dialyzer clearance calculation
    to calculate the actual dialyzer clearance for any substance
    Web Development
    dialyzer reuse
    Single-use dialyzers provide the advantage of reducing the cost of personnel, technician training on dialyzer reuse
    Web Development
    Dialyzer selection criteria
    In cases where the aim is ultrafiltration not clearance, such as hypervolemia in heart failure
    Web Development
    drug dialyzibilty factors
    The extent to which a drug is affected by dialysis is determined primarily by several physicochemical characteristics of the drug
    Web Development
    hemodialysis prescription
    As described by Daugirdas, many excellent nephrologists follow an empiric model when devising the hemodialysis prescription
    Web Development
    Influence of design.php
    Symmetric membranes, which can be derived either from cellulose or entirely from synthetic polymers, have a homogeneous configuration throughout the membrane wall
    Web Development
    Interpretation dialyzer spec
    Priming volume is how much blood needs to fill dialyzer capillaries, it consider as dead blood volume. it is varies among dialyzers
    Web Development
    hemodialysis dialyzers
    Membrane performance, as determined by the effectiveness of solute clearance and biocompatibility, is of greatest concern when choosing a dialyzer.
    Web Development
    How the solutes removed
    Solute removal in hemodialysis occurs through a combination of diffusion, convection, and adsorption
    Web Development
    types of dialyzer Membranes
    The materials most commonly used to make hollow fiber membranes include PSf, PES, cellulose triacetate (CTA), polymethylmethacrylate (PMMA), PEPA, ethylene vinyl alcohol copolymers
    Web Development
    water quality
    During haemodialysis each patient is exposed to approximately 320 to 360 litres of water per week and hence, each patient is exposed to the potential risk of chemical or microbiological contamination